The patient was a 54-year-old Caucasian woman with a history of right breast carcinoma 17 years earlier, which was treated with a right mastectomy; reconstruction included bilateral silicone implants. |
患者女、54岁、白人,病史:17年前患右侧乳腺癌,行右侧乳房切除术治疗,重建包括双侧硅胶植入。 |
The right silicone implant was subsequently replaced by a saline implant, and the patient remained well until 10 months before presentation, when an ultrasound performed because of gradual left breast enlargement revealed a peri-implant fluid collection. |
后来用盐水假体替代患者右侧硅胶假体,就诊10个月前状况良好,因左乳逐渐肿大行超声波检查发现假体周围有液体积聚。 |
The seroma was drained, and the left silicone implant was replaced by a saline implant. |
引流血清肿后,用盐水假体替代了左侧硅胶假体。 |
At the time of implant removal and replacement, the grossly unremarkable implant capsule was examined histologically and interpreted as a chronic inflammatory infiltrate with fibrosis surrounding a pseudocystic space. |
假体移除替代时,假体包膜大体无显著特征,经组织学检查解释为慢性炎症浸润伴假包囊区周围纤维化。 |
Over the next 10 months, the seroma persisted despite intermittent surgical drainage. |
其后10个月,虽然行间歇性外科引流,血清肿一直存在。 |
At the time of presentation, the seroma was again aspirated, and the fluid specimen was submitted for cytological evaluation. |
就诊时,再次引流血清肿,并对液体样本行细胞学评价。 |
A diagnosis of lymphoma was made, and this was followed by removal of the left saline implant and excision of the surrounding fibrous capsule. |
诊断为淋巴瘤,随后移除左侧盐水假体并切除其周围纤维囊。 |
Review of the initial capsulectomy specimen from 10 months earlier revealed the presence of ALK-negative ALCL. |
复查10月前的首次囊切除术标本发现存在ALK阴性的ALCL。 |
Staging evaluation by PET-CT revealed low-level fluorodeoxyglucose (FDG) uptake within the left chest wall muscle and skin overlying the left breast, consistent with postoperative changes; no other sites of FDG avidity were identified. |
PET-CT分期评价显示覆盖左乳的左胸壁肌肉皮肤内有低水平氟脱氧葡萄糖(FDG)摄取,与术后变化一致;其它部位未检出FDG亲合力。 |
A bone marrow biopsy was negative for lymphoma. |
骨髓活检为淋巴瘤阴性。 |
Ann Arbor stage was IA. |
Ann Arbor分期为IA。 |
The patient underwent four cycles of chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) followed by involved-field radiation therapy (45 Gy). |
患者接受4个疗程的环磷酰胺、多柔比星、长春新碱、泼尼松联合化疗(CHOP)随后行累及野放疗(45 Gy)。 |
She is in complete remission without evidence of lymphoma 7 months after diagnosis. |
于诊断7个月后患者完全缓解,无淋巴瘤证据。 |
The patient was a 45-year-old Caucasian woman with onset of left hip and leg pain 2 months before presentation. |
患者女、45岁、白人,就诊前2个月左髋及腿痛。 |
CBC showed mild anemia and a normal white blood cell count with an absolute monocytopenia of 175 cells/μL. |
CBC显示中度贫血,白细胞计数正常、单核细胞绝对值降低为175 个/μL。 |
She was treated initially with NSAIDs for presumed bursitis without relief then was given a 1-week prednisone taper and the pain completely resolved. |
初始应用NSAID治疗假定的滑囊炎未获缓解,随后经1周的泼尼松冲击治疗后疼痛完全消失。 |
A bone scan demonstrated three areas of abnormal uptake in the left proximal femur, and subsequent magnetic resonance imaging (MRI) confirmed three discrete areas within the left femur consistent with a marrow-infiltrating process. |
骨扫描显示左股骨近端有3处存在异常摄取,随后的核磁共振成像(MRI)证实左股骨有3处不连续的区域、符合骨髓浸润。 |
These findings were suggestive of metastatic carcinoma and prompted further radiologic evaluation. |
这些结果提示为转移癌,提示需行进一步的放射学评价。 |
A mammogram showed an increased density in the upper outer quadrant of the left breast compared with a study 3 years earlier. |
乳房造影摄片显示与3年前的一项检查相比,左侧乳腺上外象限密度增强。 |
CT scans of the chest, abdomen, and pelvis confirmed the left breast density and showed no splenomegaly or lymphadenopathy. |
胸腹部、盆腔CT扫描证实了左侧乳腺密度,未见脾肿大及淋巴结病。 |
Breast MRI confirmed a 2.5 cm left upper outer quadrant mass and also revealed a small area of enhancement in the 10 o'clock position of the right breast. |
乳腺MRI证实左侧上外象限有1肿块,右侧乳腺10点钟位置亦见一处小区域增强。 |
A stereotactic biopsy of the left breast revealed ductal carcinoma in situ (DCIS), while a subsequent core biopsy of the left proximal femur showed involvement by hairy cell leukemia. |
左侧乳腺立体定向活检发现为原位导管癌(DCIS),随后的左股骨近端中心活检显示为多毛细胞白血病累及。 |
The patient then underwent a staging posterior iliac crest bone marrow biopsy and aspirate, which also showed involvement by hairy cell leukemia, and left breast lumpectomy and left axillary sentinel lymph node biopsy. |
随后的后髂嵴骨髓活检及针吸分期亦证实有多毛细胞白血病累及,行左侧乳腺病灶切除术及左腋窝前哨淋巴结活检。 |
The lumpectomy contained extensive DCIS, as well as prominent atypical lymphoid infiltrates with morphologic and immunohistochemical features of hairy cell leukemia. |
病灶切除术标本包含广泛DCIS及明显的非典型淋巴浸润(具有多毛细胞白血病的形态学及免疫组化特征)。 |
The sentinel lymph node was negative for metastatic carcinoma, but showed a massive atypical lymphoid infiltrate, consistent with nodal involvement by hairy cell leukemia. |
前哨淋巴结无转移癌,但有大量非典型淋巴浸润,符合多毛细胞白血病累及淋巴结。 |
She was treated with a 7-day infusion of cladribine for hairy cell leukemia. |
给予患者7天克拉立滨灌注以治疗多毛细胞白血病。 |
A repeat posterior iliac crest bone marrow biopsy and aspirate performed posttreatment showed minimal residual involvement by hairy cell leukemia involving <1% of nucleated cells. |
治疗后后髂嵴骨髓活检及针吸复检显示有微量残留多毛细胞白血病累及,累及<1%的有核细胞。 |
A right breast stereotactic biopsy was then performed which revealed both invasive ductal carcinoma and DCIS. |
随后行的右侧乳腺立体定向活检显示有浸润性导管癌及DCIS。 |
The patient underwent bilateral simple mastectomies. |
患者行双侧单纯乳房切除术。 |
The left mastectomy contained residual DCIS with negative margins, as well as sparse involvement by hairy cell leukemia. |
左侧乳腺切除术包含残留DCIS及阴性边缘、以及散在的多毛细胞白血病累及部位。 |
The right mastectomy revealed both invasive ductal carcinoma and DCIS with negative margins and no evidence of involvement by hairy cell leukemia. |
右侧乳腺切除术显示为浸润性导管癌及DCIS伴阴性边缘,未见多毛细胞白血病累及证据。 |
A right axillary sentinel node biopsy was positive for metastatic carcinoma and negative for lymphoma. |
右腋窝前哨淋巴结活检显示有转移癌,未见淋巴瘤。 |
She underwent completion axillary dissection on the right and an additional 12 lymph nodes were removed, all of which were negative for carcinoma or lymphoma. |
右侧行完整腋窝淋巴结廓清术,移除了另外的12个淋巴结(均未见转移癌及淋巴瘤)。 |
After treatment with Lupron and tamoxifen, she is in complete remission from her breast carcinoma and hairy cell leukemia 14 months after diagnosis. |
经醋酸亮丙瑞林联合他莫昔芬治疗后,患者于诊断后14个月获乳腺癌及多毛细胞白血病完全缓解。 |